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Antigenic Specificity | TIP47 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TIP47 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TIP47 from other sources has not been determined. Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist. |
Immunogen | Anti-TIP47 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide from near the N-terminus of human TIP47. |
Other Names | TIP47 Antibody, PP17, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, Perilipin-3, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17, PLIN3, M6PRBP1 |
Gene, Accession # | PLIN3, Gene ID: 26762, NCBI: NP_036338, UniProt: Q96D42 |
Catalog # | 600-401-FF2 |
Price | $475 |
Order / More Info | TIP47 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |