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Antigenic Specificity | Paxillin |
Clone | PXC-10 |
Host Species | Mouse |
Reactive Species | human, mouse, rat, chicken |
Isotype | IgG1 |
Format | Protein A purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Paxillin antibody was purified from mouse ascites by protein A chromatography. This product reacts with human, mouse, rat, and chicken. Cross reactivity with Paxillin from other sources has not been determined. The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells. This antibody is suitable for researchers interested in growth factors and signal transduction. |
Immunogen | Paxillin antibody was produced in mice by repeated immunizations with recombinant protein corresponding to the C-terminal part of chicken paxillin (amino acids 305-559). |
Other Names | Paxillin antibody, PXN |
Gene, Accession # | PXN, Gene ID: 5829, NCBI: NP_001074324.1, UniProt: P49023 |
Catalog # | 200-301-P44 |
Price | $485 |
Order / More Info | Paxillin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |