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Antigenic Specificity | Histone H3 K4me3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, C. elegans |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 50 µg |
Concentration | 0.70 mg/ml |
Applications | Chip, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Histone H3 [Trimethyl Lys4] was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3.2. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined. H3K4Me3 is a common epigenetic modification that occurs in close proximity to nearly 2/3 of human gene promoters, and seems to balance another modification, H3K27Me3. These two modifications work in tandem to differentiate and/or maintain stem cells. Zygotic cells are activated in the most part by H3K4Me3; whereas, cancer is associated with disrupted associations between K3K4Me3 and ING1. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research. |
Immunogen | Histone H3 [Trimethyl Lys4] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic trimethylated peptide surrounding Lysine 4 of human Histone H3.2. |
Other Names | rabbit anti-Histone H3 trimethyl Lys4 antibody, H3.3B, H3.3AH3F3H3F3B, H3 histone, family 3A, histone H3.3, MGC87783, MGC87782, H3K4me3 |
Gene, Accession # | HIST2H3C, Gene ID: 126961, NCBI: NP_001005464, UniProt: Q71DI3 |
Catalog # | 600-401-I59 |
Price | $495 |
Order / More Info | Histone H3 K4me3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |