Histone H3 K4me3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityHistone H3 K4me3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, C. elegans
Isotypen/a
Formatimmunoaffinity purified
Size50 µg
Concentration0.70 mg/ml
ApplicationsChip, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-Histone H3 [Trimethyl Lys4] was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human Histone H3.2. A BLAST analysis was used to suggest cross-reactivity with Human, mouse, and C. elegans. Predicted to react with many species including rat, chicken, Xenopus, Drosophila, and plant based on 100% sequence homology. Cross-reactivity with Histone H3 from other sources has not been determined. H3K4Me3 is a common epigenetic modification that occurs in close proximity to nearly 2/3 of human gene promoters, and seems to balance another modification, H3K27Me3. These two modifications work in tandem to differentiate and/or maintain stem cells. Zygotic cells are activated in the most part by H3K4Me3; whereas, cancer is associated with disrupted associations between K3K4Me3 and ING1. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research.
ImmunogenHistone H3 [Trimethyl Lys4] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic trimethylated peptide surrounding Lysine 4 of human Histone H3.2.
Other Namesrabbit anti-Histone H3 trimethyl Lys4 antibody, H3.3B, H3.3AH3F3H3F3B, H3 histone, family 3A, histone H3.3, MGC87783, MGC87782, H3K4me3
Gene, Accession #HIST2H3C, Gene ID: 126961, NCBI: NP_001005464, UniProt: Q71DI3
Catalog #600-401-I59
Price$495
Order / More InfoHistone H3 K4me3 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

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Technical Support: tech@rockland.com

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