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Antigenic Specificity | RBBP8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-RBBP8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with RBBP8 from other sources has not been determined. RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway. |
Immunogen | Anti-RBBP8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the internal region of human RBBP8. |
Other Names | RBBP8 Antibody, RIM, COM1, CTIP, JWDS, SAE2, SCKL2, DNA endonuclease RBBP8, CtBP-interacting protein, CtIP |
Gene, Accession # | RBBP8, Gene ID: 5932, NCBI: NP_976037, UniProt: Q99708 |
Catalog # | 600-401-DW9 |
Price | $475 |
Order / More Info | RBBP8 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |