F4/80 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | F4/80 |
| Clone | BM8 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | phycoerythrin (RPE) conjugate |
| Size | 100 µg |
| Concentration | 0.2mg/mL |
| Applications | Flow Cytometry, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Phycoerythrin conjugated F4/80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse F4/80. Cross reactivity with F4/80 from other sources has not been tested. Anti-F4/80 is conjugated with PE under optimal conditions and the solution is free of unconjugated PE. F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8 T cells-mediated peripheral tolerance. |
| Immunogen | Anti-F4/80 Antibody (Monoclonal) was produced by repeated immunizations with murine macrophages. |
| Other Names | EMR1, Ly71, EGF-TM7, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor, Gpf480, Adgre1 |
| Gene, Accession # | Adgre1, Gene ID: 13733, NCBI: NP_034260.1, UniProt: Q61549 |
| Catalog # | 200-508-L55 |
| Price | $519 |
| Order / More Info | F4/80 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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