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Antigenic Specificity | ZIP7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZIP7 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ZIP7 from other sources has not been determined. The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous. |
Immunogen | Anti-ZIP7 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human ZIP7. |
Other Names | ZIP7 Antibody, KE4, HKE4, ZIP7, RING5, H2-KE4, D6S115E, D6S2244E, Zinc transporter SLC39A7, Histidine-rich membrane protein Ke4 |
Gene, Accession # | SLC39A7, Gene ID: 7922, NCBI: NP_001070984.1, UniProt: Q92504 |
Catalog # | 600-401-GF2 |
Price | $475 |
Order / More Info | ZIP7 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |