Edit |   |
---|---|
Antigenic Specificity | Calretinin |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | rat, guinea pig |
Isotype | n/a |
Format | Protein A purified |
Size | 100 µL |
Concentration | Contains antibody for 10 mini-Western blots at suggested dilution |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | |
Description | Anti-Calretinin Antibody is directed against guinea pig Calretinin protein. The antibody was purified from monospecific antiserum by Protein A chromatography. Anti-Calretinin antibody reacts with Calretinin from rat and guinea pig sources. Cross reactivity with Calretinin from other species has not been determined. However, reactivity is also expected from the following species based on 100% sequence homology: human, mouse, non-human primates. Calretinin antibody reacts with calretinin which is a calcium-binding protein involved in calcium signaling. Calretinin is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium. Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas. Anti-Calretinin antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
Immunogen | Anti-Calretinin Antibody was produced by repeated immunizations with native guinea pig calretinin. |
Other Names | CR, Calb2, CAB29, Calretinin |
Gene, Accession # | Calb2, Gene ID: 117059, NCBI: NP_446440.1, UniProt: P47728 |
Catalog # | 200-601-D13 |
Price | $475 |
Order / More Info | Calretinin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 25469233 |