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Antigenic Specificity | Aha1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100 µL |
Concentration | 85 mg/mL |
Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Aha 1 Antibody was purified by Protein A chromatography. A BLAST analysis was used to suggest cross-reactivity with Aha 1 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Aha1 from other sources has not been determined. Heat Shock research. Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors. |
Immunogen | Aha1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with Mouse Aha1. |
Other Names | Aha1, SHSA1, HspC322, p38, Activator of 90 kDa heat shock protein ATPase homolog 1 |
Gene, Accession # | Ahsa1, Gene ID: 217737, NCBI: NP_666148.1, UniProt: Q8BK64 |
Catalog # | 100-401-E82 |
Price | $445 |
Order / More Info | Aha1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 23798910 |