Histone H3 K27 me2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Histone H3 K27 me2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 50 µg |
| Concentration | 2.63 mg/ml |
| Applications | ELISA, Chip, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-H3K27me2 Antibody was purified by affinity purification. This product reacts with human Histone 3 dimethyl Lys27. Cross reactivity with H3K27me2 from species other than human is not known. Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called ``histone code''. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Levels of H3K27 dimethylation are higher in silent genes than in active genes suggesting that this histone modification is associated with transcriptional repression. Anti-H3K27me2 Antibody is ideal for research in Chromatin Remodeling, Epigenetics and Gene Expression. |
| Immunogen | Anti-H3K27me2 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide of human histone H3, dimethylated at lysine 27. |
| Other Names | Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/e, Histone H3/f, Histone H3/g, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l |
| Gene, Accession # | HIST1H3A, Gene ID: 3020, NCBI: NP_002098, UniProt: P84243 |
| Catalog # | 600-401-V34 |
| Price | $475 |
| Order / More Info | Histone H3 K27 me2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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