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Antigenic Specificity | ZGPAT |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZGPAT Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Multiple isoforms of ZGPAT are known to exist. The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT. |
Immunogen | Anti-ZGPAT antibody was prepared from chicken egg fractions produced by repeated immunizations with a 15 amino acid synthetic peptide near the C-terminus of human ZGPAT. |
Other Names | ZGPAT Antibody, ZIP, ZC3H9, GPATC6, GPATCH6, ZC3HDC9, KIAA1847, ZIP, Zinc finger CCCH-type with G patch domain-containing protein, G patch domain-containing protein 6 |
Gene, Accession # | ZGPAT, Gene ID: 84619, NCBI: NP_001076582.1, UniProt: Q8N5A5 |
Catalog # | 200-901-GD6 |
Price | $475 |
Order / More Info | ZGPAT Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |