TOLLIP Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTOLLIP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Western Blot
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DescriptionAnti-TOLLIP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TOLLIP from other sources has not been determined. Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.
ImmunogenAnti-TOLLIP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the internal region of human TOLLIP.
Other NamesTOLLIP Antibody, IL-1RAcPIP, Toll-interacting protein
Gene, Accession #TOLLIP, Gene ID: 54472, NCBI: NP_001305441.1, UniProt: Q9H0E2
Catalog #600-401-FL7
Price$475
Order / More InfoTOLLIP Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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