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Antigenic Specificity | MATN3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-MATN3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MATN3 from other sources has not been determined. Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms. |
Immunogen | Anti-MATN3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 13 amino acid synthetic peptide from near the C-terminus of human MATN3. |
Other Names | MATN3 Antibody, HOA, OS2, EDM5, DIPOA, OADIP, Matrilin-3 |
Gene, Accession # | MATN3, Gene ID: 4148, NCBI: AAI39908, UniProt: O15232 |
Catalog # | 600-401-CR4 |
Price | $475 |
Order / More Info | MATN3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |