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Antigenic Specificity | ACSL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ACSL1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of ACSL1 are known to exist; this antibody will detect all three isoforms. Long-chain acyl coenzyme A synthetase 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids in an ATP-dependent manner. ACSL1 is a member of a family of long-chain acyl-CoA synthetases which differ in substrate preference, tissue expression, and subcellular localization. In mouse, ASCL1 is the major acyl-CoA enzyme in the heart, providing 60-90% of heart ATP. Loss of ASCL1 either globally or in heart ventricles resulted in impaired fatty acid oxidation, activation of the mammalian target of rapamycin (mTOR), and cardiac hypertrophy. |
Immunogen | Anti- ACSL1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the internal region of human ACSL1. |
Other Names | ACSL1 Antibody, ACS1, LACS, FACL1, FACL2, LACS1, LACS2, Long-chain-fatty-acid--CoA ligase 1, Acyl-CoA synthetase 1, ACS1 |
Gene, Accession # | ACSL1, Gene ID: 2180, NCBI: NP_001986, UniProt: P33121 |
Catalog # | 600-401-X65 |
Price | $475 |
Order / More Info | ACSL1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |