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Antigenic Specificity | TNFSF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TNFSF4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of TNFSF4 are known to exist; this antibody will detect both isoforms. The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFN-gamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance. |
Immunogen | Anti-TNFSF4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the C-terminus of human TNFSF4. |
Other Names | TNFSF4 Antibody, GP34, CD252, OX4OL, TXGP1, CD134L, OX-40L, Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40L |
Gene, Accession # | TNFSF4, Gene ID: 7292, NCBI: NP_001284491.1, UniProt: P23510 |
Catalog # | 600-401-FL1 |
Price | $475 |
Order / More Info | TNFSF4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |