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Antigenic Specificity | Cathepsin D |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian |
Isotype | n/a |
Format | epitope affinity purified |
Size | 600 µg |
Concentration | 3 mg/ml |
Applications | WB, IF, IHC-P, IHC-F, IEM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RRID: AB_2333119. Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. This antibody gives a positive signal in the following human (Jurkat, HT1080, HUH, MDA-MB-231, ARPE19, SH-SY5Y), canine (MDCK) and monkey (COS-7) whole cell lysates. |
Immunogen | Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli. |
Other Names | ceroid-lipofuscinosis, CLN10; CPSD, CTSD, lysosomal aspartyl protease, lysosomal aspartyl peptidase, neuronal 10 antibody. |
Gene, Accession # | Accession: ENSG00000117984 |
Catalog # | AB0043-200 |
Price | 320 € |
Order / More Info | Cathepsin D Antibody from SICGEN ANTIBODIES |
Product Specific References | 1. Romagnoli M, Bresson L, Di-Cicco A, et al. Development 2020 Jan. PMID:31988184, 2. Pelkonen L, Sato K, Reinisalo M, et al. Mol Pharm 2017 Mar 6. PMID:28112518 |