SARS-CoV-2 Nucleocapsid protein (R203K, G204R), His Tag from ACROBIOSYSTEMS USA
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| Product Name | SARS-CoV-2 Nucleocapsid protein (R203K, G204R), His Tag |
| Description | SARS-CoV-2 Nucleocapsid protein (R203K, G204R), His Tag (NUN-C52Hg) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1 (R203K, G204R)). The nucleocapsid protein is consisted of the N-terminal RNA-binding domain (NTD) and the C-terminal dimerization domain (CTD), divided by a central serine/arginine-rich (SR)-linker responsible for phosphorylation. The mutations (R203K, G204R) were identified on the SR-linker on the nucleocapsid protein of SARS-CoV-2 variants. Phosphorylation of this SR-link motif in SARS-CoV modulates nucleocapsid multimerization, translational inhibitory activity and cellular localization. The co-occuring mutations R203K and G204R may decrease the overall structural flexibility of SARS-COV-2 N protein. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity: 90% |
| Size | 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | recombinant protein |
| Gene, Accession, CAS # | Accession: QHO62115.1 (R203K, G204R) |
| Catalog # | NUN-C52Hg-100ug |
| Price | $400 |
| Order / More Info | SARS-CoV-2 Nucleocapsid protein (R203K, G204R), His Tag from ACROBIOSYSTEMS USA |
| Product Specific References | n/a |
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