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Product Name | SARS-CoV-2 Spike Trimer Protein, His Tag (BA.3/Omicron) (MALS verified) |
Description | SARS-CoV-2 Spike Trimer, His Tag (BA.3/Omicron) (SPN-C522c) is expressed from human 293 cells (HEK293). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.3; GISAID clade: GRA; Nextstrain clade: 21M). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 137.8 kDa. The protein migrates as 160-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity: 95% |
Size | 100mg |
Concentration | n/a |
Applications | n/a |
Other Names | recombinant protein |
Gene, Accession, CAS # | Accession: QHD43416.1 (A67V,H69del,V70del,T95I,G142D,V143del,Y144del,Y145del,N211del,L212I,G339D,S371F,S373P,S375F,D405N,K417N,N440K,G446S,S477N,T478K,E484A,Q493R,Q498R,N501Y,Y505H,D614G,H655Y, N679K,P681H,N764K,D796Y,Q954H,N969K,R683A, R685A, F817P, A892P, A899P, A |
Catalog # | SPN-C522c-100mg |
Price | $286720 |
Order / More Info | SARS-CoV-2 Spike Trimer Protein, His Tag (BA.3/Omicron) (MALS verified) from ACROBIOSYSTEMS USA |
Product Specific References | n/a |
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