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Product Name | SARS-CoV-2 Spike Trimer Protein (T95I, G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H), His Tag (MALS verified) |
Description | SARS-CoV-2 Spike Trimer, His Tag (SPN-C52Hr) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations (T95I, G142D, E154K, L452R, E484Q, D614G, P681R) were identified in the SARS-CoV-2 Kappa variant (Pango lineage: B.1.617.1; other names: 21A/S:154K). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 138.2 kDa. The protein migrates as 150-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity: 95% |
Size | 50ug |
Concentration | n/a |
Applications | n/a |
Other Names | recombinant protein |
Gene, Accession, CAS # | Accession: QHD43416.1 |
Catalog # | SPN-C52Hr-50ug |
Price | $450 |
Order / More Info | SARS-CoV-2 Spike Trimer Protein (T95I, G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H), His Tag (MALS verified) from ACROBIOSYSTEMS USA |
Product Specific References | n/a |
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