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Product Name | A-839977 |
Description | A-839977 is a potent and selective antagonist of P2X7 receptors, shown to inhibit BzATP-induced Ca2+ responses at human, rat and mouse P2X7 receptors with IC50 values of 20 nM, 42 nM and 150 nM, respectively. A-839977 produces significant anti-nociception and anti-hyperalgesia (ED50 = 40-100µmol/kg) in animal models of inflammatory pain1. Synthetic. Purity >96%. MW: 413.26 |
Size | 10 mg |
Concentration | 1-50 nM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 870061-27-1 |
Catalog # | A-470 |
Price | please inquire |
Order / More Info | A-839977 from ALOMONE LABS |
Product Specific References | n/a |
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