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Product Name | A-192621 |
Description | A-192621 is a selective antagonist of ET-B endothelin receptors, inhibiting ET-1 binding to ETA and ET-3 binding to ETB receptors with IC50 values of 4280 nM and 4.5 nM, respectively1.In vivo, A-192621 inhibits ETB-mediated dilatory and pressor responses induced by Sarafotoxin 6c (ED50 = 30 mg/kg), and causes an elevation of arterial blood pressure and plasma ET-1 level2. Synthetic. Purity >97% (HPLC). MW: 558.68 |
Size | 1 mg |
Concentration | 0.1-10 nM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 195529-54-5 |
Catalog # | A-360 |
Price | please inquire |
Order / More Info | A-192621 from ALOMONE LABS |
Product Specific References | n/a |
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