Metabotropic Glutamate Receptor 1 ELISA Kit from ANTIBODIES-ONLINE GmbH

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Product NameMetabotropic Glutamate Receptor 1 ELISA Kit
DescriptionProduct Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of GRM1 in human tissue homogenates, cell lysates.
Target Information: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms\, some of which may have distinct functions. [provided by RefSeq, Jul 2008].
Size10 x 96 tests
Concentrationn/a
ApplicationsELISA
Other NamesGPRC1A|MGLU1|MGLUR1|SCAR13|metabotropic glutamate receptor 1|glutamate metabotropic receptor 1|GRM1|Glutamate Receptor, Metabotropic 1|4930455H15Rik|ENSMUSG00000075319|Gm10828|nmf373|rcw|wobl|G protein coupled receptor|family C|group 1|member A|G protein-coupled receptor|G protein coupled receptor family C group 1 member A|fj39d05|si:ch211-51a19.1|wu:fj39d05|glutamate receptor, metabotropic 1a|grm1a|GB18621|Glura|mGlutR|metabotropic glutamate receptor A|mGlutR1
Gene, Accession, CAS #Gene ID: 2911
Catalog #ABIN7070174
Price$6576
Order / More InfoMetabotropic Glutamate Receptor 1 ELISA Kit from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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