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Product Name | Sisunatovir HCl |
Description | Sisunatovir, also known as RV521, is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. RV521 exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Oral bioavailability in preclinical species ranged from 42 to > 100% with evidence of highly efficient penetration into lung tissue. In healthy adult human volunteers experimentally infected with RSV, a potent antiviral effect was observed with a significant reduction in viral load and symptoms compared to placebo. MW: 482.91 |
Size | 100 mg, 250 mg, 1 g |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 1903763-83-6 |
Catalog # | orb757612 |
Price | please inquire |
Order / More Info | Sisunatovir HCl from BIORBYT LTD. |
Product Specific References | n/a |
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