MK-0591 from CAYMAN CHEMICAL COMPANY
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| Product Name | MK-0591 |
| Description | An inhibitor of FLAP (IC50 = 1.6 nM for the human enzyme); inhibits LTB4 biosynthesis in A23187-stimulated isolated rat neutrophils (IC50 = 6 nM) but does not inhibit 5-LO in a cell-free assay (IC50 = > 4 µM for the rat enzyme); prevents increases in airway resistance and decreases in dynamic compliance in Ascaris antigen-induced squirrel monkeys at 0.3 and 1 mg/kg; decreases proteinuria and reduces decreases in renal LTC4 synthase activity in a rat model of nephrotoxic rabbit serum-induced glomerulonephritis at 60 mg/kg; induces apoptosis in LNCaP cells at 8 µM |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | L-686,708|Quiflapon |
| Gene, Accession, CAS # | CAS: 136668-42-3 |
| Catalog # | 37322-10 |
| Price | $498.00 |
| Order / More Info | MK-0591 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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