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Product Name | 10074-A4 |
Description | An inhibitor of the protein-protein interaction between c-Myc and Max; inhibits c-Myc and Max heterodimerization at 5 µM and the proliferation of Rat1 and TGR-1 rat fibroblasts but not TGR-1 Myc knockout fibroblasts at 32 µM; reduces the expression of the gene encoding ODC and induces cell cycle arrest at the G0/G1 phase in Myc-overexpressing Rat1 cells at 32 µM; preincubation of 10074-A4 at 32 µM with Myc-overexpressing Rat1 cells in vitro reduces tumor growth of the same cells in a mouse xenograft model. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 10074A4 cMyc Rat-1 TGR1 |
Gene, Accession, CAS # | CAS: 312631-87-1 |
Catalog # | 37486-1 |
Price | $36.00 |
Order / More Info | 10074-A4 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |