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Product Name | Netropsin (hydrochloride) |
Description | A DNA minor groove binder; binds A/T rich regions of DNA (Ka = 4.9 x 105 M-1 for poly(dA)poly(dT) DNA); inhibits topoisomerase II (IC90 = 200 µM in a cell-free assay); inhibits teniposide-induced crosslinks in nuclei from 935.1 cells (IC50 = 65 µM); active against S. aureus, S. typhosa, K. pneumoniae, and A. aerogenes (MICs = 5, 10, 10, and 5 µg/ml, respectively); inhibits viral plaque formation in Shope fibroma virus- or vaccinia virus-infected BS-C-1 host cells at 75 µg/ml; increases survival in a mouse model of endotoxemia induced by LPS at 25 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Congocidine|Sinanomycin |
Gene, Accession, CAS # | CAS: 18133-22-7 |
Catalog # | 33727-10 |
Price | $152.00 |
Order / More Info | Netropsin (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |