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Product Name | A011 |
Description | An inhibitor of ATM kinase (IC50 = 1 nM); selective for ATM over a panel of 408 additional kinases at 10 µM; inhibits the growth of SW620 and HCT116 cells (IC50s = 0.14 and 0.91 µM, respectively); enhances irinotecan-induced cell death in SW620 and HCT116 cells at 10, 30, and 100 nM; increases irradiation-induced cell death in SW620 cells; increases irinotecan-induced reductions in tumor growth in an SW620 mouse xenograft model at 5 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | A0 11 A 011 SW 620 HCT 116 topo isomerase |
Gene, Accession, CAS # | n/a |
Catalog # | 39183-5 |
Price | $267.00 |
Order / More Info | A011 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |