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Product Name | ARN726 |
Description | An NAAA inhibitor (IC50s = 27 and 63 nM for the human and rat enzyme, respectively); selective for NAAA over FAAH and acid ceramidase (IC50s = >100 and 12.5 µM, respectively), as well as a panel of 28 enzymes at 10 µM; decreases lung myeloperoxidase activity and pleural exudate TNF-α levels in a mouse model of carrageenan-induced lung inflammation from 1-30 mg/kg; inhibits NAAA and reverses complete Freund's adjuvant-induced decreases in PEA and OEA levels in inflamed paw tissue in a rat model of arthritis |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ARN 726 NA AA N AAA FA AH myelo-peroxidase TNFα P EA O |
Gene, Accession, CAS # | CAS: 1628343-77-0 |
Catalog # | 24259-25 |
Price | $456.00 |
Order / More Info | ARN726 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |