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Product Name | LMTK3 Inhibitor C28 |
Description | A multi-kinase inhibitor; inhibits LMTK3, Clk2, DYRK1α, HIPK2, and IRAK4 (IC50s = 67, 5, 6, 48, and 41 nM), among others; selective for these kinases over a panel of 122 kinases at 1 µM; induces proteasomal degradation of LMTK3 in MCF-7, T47D, and MDA-MB-231 cells at 5 or 10 µM; reduces the levels of IRAK4, ERα, phosphorylated TrkA, and HIPK2 in T47D cells at 10 µM; induces apoptosis in MCF-7, T47D, and MDA-MB-231 cells at 10 µM; reduces tumor growth and volume in an MDA-MB-231 mouse xenograft model at 10 mg/kg per day |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Lemur Tyrosine Kinase 3 Inhibitor 1|Lemur Tyrosine Kinase 3-IN-1|Lemur Tyrosine Kinase Inhibitor C28|Lemur Tyrosine Kinase-IN-C28|LMTK3 Inhibitor 1|LMTK3-IN-1|LMTK3-IN-C28 |
Gene, Accession, CAS # | CAS: 2764850-23-7 |
Catalog # | 41877-100 |
Price | $910.00 |
Order / More Info | LMTK3 Inhibitor C28 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |