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Product Name | ACE2 Inhibitor Screening Assay Kit |
Description | Cayman's ACE2 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for testing potential inhibitors of human ACE2. The assay uses an ACE2-specific fluorogenic substrate, Mca-APK (Dnp). ACE2 cleaves this substrate generating free Mca, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 320 and 405 nm, respectively. The potent and reversible ACE2 inhibitor MLN-4760 is included as a positive control. Human ACE2 plays an important role in regulating blood pressure. It is also known to bind SARS-CoV-2 spike. This assay can be used as a counter-screen for potential drug candidates to ensure they do not interfere with the normal physiological functions of ACE2. |
Size | 96 Well |
Concentration | n/a |
Applications | n/a |
Other Names | ACEH|ACE-related Carboxypeptidase|Angiotensin-converting Enzyme 2|Angiotensin-converting Enzyme Homolog|Metalloprotease MPROT15 |
Gene, Accession, CAS # | n/a |
Catalog # | 502100-96WELLS |
Price | $458.00 |
Order / More Info | ACE2 Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |