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Product Name | VU0155041 (sodium salt) |
Description | A selective positive allosteric modulator of mGluR4 (EC50 = 2.5 µM in a thallium flux assay); has no effect on radioligand binding at 67 G protein-coupled receptors, ion channels, and transporters; lacks antagonist activity at NMDA receptors in striatal medium spiny neurons at a concentration of 10 µM; decreases haloperidol-induced catalepsy and reverses reserpine-induced askinesias in rat models of Parkinson's disease; restores social behavior in the Oprm-/- mouse model of autism; decreases anxiety-like behavior in the elevated plus maze in mice |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | VU-0155041 1093757-42-6 mGluR-4 GPR N?methyl?D?aspartate aspartic |
Gene, Accession, CAS # | CAS: 1259372-69-4 |
Catalog # | 21775-50 |
Price | $169.00 |
Order / More Info | VU0155041 (sodium salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |