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Product Name | FT113 |
Description | A FASN inhibitor (IC50 = 213 nM); inhibits the proliferation of PC3 and MV4-11 cells (IC50s = 47 and 26 nM, respectively); inhibits FASN activity in a 14C-acetate incorporation assay using BT474 cells (IC50 = 90 nM); reduces tumor growth and increases intratumoral levels of the FASN substrate malonyl-CoA in an MV4-11 mouse xenograft model at 25 and 50 mg/kg; inhibits infection of HEK293T-hACE2 cells with SARS-CoV-2-mNG (EC50 = 17 nM) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | FT 113 PC 3 MV411 MV 411 BT 474 HEK293 T HEK 293T HEK293ThACE2 HEK293ThACE 2 SARSCoV2mNG SARSCoV CoV2 malonylCoA |
Gene, Accession, CAS # | CAS: 1630808-89-7 |
Catalog # | 37545-10 |
Price | $122.00 |
Order / More Info | FT113 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |