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Product Name | cGAS Inhibitor Screening Assay Kit |
Description | Cayman's cGAS Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human cGAS, which is a cytosolic dsDNA sensor that detects microbial pathogens. The assay directly measures 2'3'-cGAMP produced by cGAS in the presence of DNA, ATP, and GTP. The cyclic dinucleotide product of that reaction is quantified via ELISA using a 2'3'-cGAMP-specific antiserum. The cGAS inhibitor CU-76 is included as a positive control.,,,The ELISA portion of Cayman's cGAS Inhibitor Screening Assay Kit is a competitive assay with a range of 4.57-10,000 pM, a midpoint of approximately 300 pM (50% B/B0), and a sensitivity (80% B/B0) of approximately 50 pM. |
Size | 96 Solid |
Concentration | n/a |
Applications | ELISA |
Other Names | 2'3'-cGAMP Synthase|C6orf150|Cyclic GMP-AMP Synthase |
Gene, Accession, CAS # | n/a |
Catalog # | 701930-96SOLIDWELLS |
Price | $617.00 |
Order / More Info | cGAS Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |