LMTK3 Inhibitor C28 from CAYMAN CHEMICAL COMPANY

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Product NameLMTK3 Inhibitor C28
DescriptionA multi-kinase inhibitor; inhibits LMTK3, Clk2, DYRK1α, HIPK2, and IRAK4 (IC50s = 67, 5, 6, 48, and 41 nM), among others; selective for these kinases over a panel of 122 kinases at 1 µM; induces proteasomal degradation of LMTK3 in MCF-7, T47D, and MDA-MB-231 cells at 5 or 10 µM; reduces the levels of IRAK4, ERα, phosphorylated TrkA, and HIPK2 in T47D cells at 10 µM; induces apoptosis in MCF-7, T47D, and MDA-MB-231 cells at 10 µM; reduces tumor growth and volume in an MDA-MB-231 mouse xenograft model at 10 mg/kg per day
Size50 mg
Concentrationn/a
Applicationsn/a
Other NamesLemur Tyrosine Kinase 3 Inhibitor 1|Lemur Tyrosine Kinase 3-IN-1|Lemur Tyrosine Kinase Inhibitor C28|Lemur Tyrosine Kinase-IN-C28|LMTK3 Inhibitor 1|LMTK3-IN-1|LMTK3-IN-C28
Gene, Accession, CAS #CAS: 2764850-23-7
Catalog #41877-50
Price$520.00
Order / More InfoLMTK3 Inhibitor C28 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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