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Product Name | VX-702 |
Description | A third generation inhibitor of p38 MAP kinases, binding to both p38α and p38β (Kd = 3.7 and 17 nM, respectively); inhibits IL-6, IL-1β, and TNF-α production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml, respectively |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 479543-46-9 inhibitors inflammation autoimmune diseases arthritis cells signaling VX702 VX 702 inhibits inhibitions p38 mitogen activated proteins MAPs kinases IL-6 IL6 IL 6 IL-1β IL1β IL 1β TNFs TNF-α TNFα LPS thrombin U46619 U-46619 U 46619 thrombin collagen MAPK |
Gene, Accession, CAS # | CAS: 745833-23-2 |
Catalog # | 13108-25 |
Price | $107.00 |
Order / More Info | VX-702 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |