WAY-169916 from CAYMAN CHEMICAL COMPANY
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| Product Name | WAY-169916 |
| Description | A pathway-selective estrogen receptor ligand; binds to human ERα and ERβ (IC50 = 3 nM for both); inhibits IL-1β-induced NF-κB reporter activity in HAECT-1 cells expressing human ERα (IC50 = 93 nM); reduces 17β-estradiol-induced increases in CK activity in HAECT-1 cells at 1 µM; reduces high-fat diet-induced hepatic NF-κB activity and inflammatory gene expression in ovariectomized rats at 10 mg/kg; inhibits chronic diarrhea, as well as intestinal ulceration and inflammatory cell infiltration in an HLA-B27 transgenic rat model of IBD; reduces infarct size in an ovariectomized rabbit model of coronary artery occlusion-induced ischemia and reperfusion injury at 1 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | WAY169916 IL1β NFκB HAECT1 HLAB27 Allyl yl]benzene |
| Gene, Accession, CAS # | CAS: 669764-18-5 |
| Catalog # | 35842-5 |
| Price | $127.00 |
| Order / More Info | WAY-169916 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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