MK-0974 from CAYMAN CHEMICAL COMPANY
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| Product Name | MK-0974 |
| Description | A CGRP receptor antagonist (Ki = 0.77 µM); binds selectively to the human CGRP receptor complex over the adrenomedullin receptor complexes in HEK293 cells (Kis = >100 and 29 µM for CRLR with RAMP2 and 3, respectively); inhibits CGRP-induced cAMP accumulation in HEK293 cells expressing the CGRP receptor complex (IC50 = 2.2 nM); reduces CGRP-induced vasodilation in isolated human meningeal arteries; inhibits vasodilation induced by topical application of capsaicin in rhesus monkeys (EC50 = 127 nM) |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | MK0974 telcagepant RAMP-1 2 3 HEK-293 |
| Gene, Accession, CAS # | CAS: 781649-09-0 |
| Catalog # | 23960-10 |
| Price | $535.00 |
| Order / More Info | MK-0974 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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