VX-745 from CAYMAN CHEMICAL COMPANY
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| Product Name | VX-745 |
| Description | A p38α MAPK inhibitor (IC50 = 9 nM); selective for p38α over p38β MAPK (Ki = 220 nM) as well as ERK, JNK, and a panel of 50 kinases at 2 µM; inhibits LPS-induced production of IL-1β and TNF-α in isolated human PBMCs (IC50s = 45 and 51 nM, respectively); reduces disease severity in a type II collagen-induced mouse model of arthritis at 10 mg/kg |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Neflamapimod |
| Gene, Accession, CAS # | CAS: 209410-46-8 |
| Catalog # | 18075-50 |
| Price | $684.00 |
| Order / More Info | VX-745 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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