Edit |   |
---|---|
Product Name | VX-765 |
Description | A prodrug form of VRT-043198; inhibits LPS-induced increases in serum IL-1β levels in mice at 50, 100, and 200 mg/kg; reduces oxazolone-induced ear edema and levels of IL-1β, IL-18, and IFN-γ in ear tissue in an oxazolone-sensitized mouse model of delayed-type hypersensitivity; reduces forepaw inflammation in a mouse model of collagen-induced arthritis in a dose-dependent manner; decreases seizure duration and the number of seizures in a mouse model of acute seizures induced by hippocampal kainic acid injection at ≥50 mg/kg, as well as delays the onset of seizures at 100 and 200 mg/kg; reduces the aggregated duration of epileptic activity in a mouse model of chronic epilepsy |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Belnacasan |
Gene, Accession, CAS # | CAS: 273404-37-8 |
Catalog # | 28825-50 |
Price | $448.00 |
Order / More Info | VX-765 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |