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Product Name | CC-122 |
Description | A pleiotropic pathway modifier with anticancer activity; binds to cereblon in U266 multiple myeloma cell extracts; induces recruitment and degradation of Aiolos and Ikaros in TMD8, OCI-LY10, and Karpas 422 DLBCL cells at 0.1, 1, and 10 µM; decreases proliferation and induces apoptosis ABC and GCB DLBCL cell lines from 0.1-10,000 nM; stimulates IL-2 production in mouse primary T cells; decreases tumor levels of Aiolos and Ikaros and reduces tumor growth in OCI-LY10 ABC DLBCL and WSU-DLCL2 GCB DLBCL mouse xenograft models |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Avadomide |
Gene, Accession, CAS # | CAS: 1015474-32-4 |
Catalog # | 26257-5 |
Price | $280.00 |
Order / More Info | CC-122 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |