Edit |   |
---|---|
Product Name | TM5441 |
Description | A PAI-1 inhibitor; decreases survival of HT1080, HCT116, Daoy, MDA-MB-231, and Jurkat cancer cells (IC50s = 13.9-51.1 µM); inhibits branching of HUVECs (50 µM); disrupts tumor vasculature in mouse xenograft models (20 mg/kg per day); prevents L-NAME-induced hypertension and cardiac hypertrophy; protects against NAFLD in mice induced by high-fat diet |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1594101-42-4 TM-5441 PAI1 HT-1080 HCT-116 MDAMB231 LNAME |
Gene, Accession, CAS # | CAS: 1190221-43-2 |
Catalog # | 22965-5 |
Price | $116.00 |
Order / More Info | TM5441 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |