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Product Name | Metixene (hydrochloride hydrate) |
Description | A muscarinic acetylcholine receptor antagonist (Ki = 15 nM for the rat receptor); inhibits bovine AChE by 43% at 10 µM and BChE (IC50 = 1.6 µM for the horse enzyme) in cell-free assays; reduces the proliferation of P388 and P388/ADR leukemia cells (EC50s = 10 and 12 µM, respectively); induces apoptosis in BT474 and MDA-MB-231 cancer cells at 15 µM and induces autophagy in the same cells at 10 µM; decreases tumor weight and volume and improves survival in an MDA-MB-231 breast cancer mouse xenograft model at 1 mg/kg three times per week |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Methixine |
Gene, Accession, CAS # | CAS: 7081-40-5 |
Catalog # | 39825-10 |
Price | $200.00 |
Order / More Info | Metixene (hydrochloride hydrate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |