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Product Name | VU6036720 (hydrochloride) |
Description | An inhibitor of heteromeric Kir4.1/5.1 channels (IC50 = 0.24 µM); selective for Kir4.1/5.1 channels over a variety of homomeric Kir channels, including Kir4.1 (IC50 = >10 µM), as well as heteromeric Kir3.1/3.2, Kir3.1/3.4, Kir6.2/SUR1, and Kir6.1/SUR2b channels at 30 µM but does inhibit the voltage-gated potassium channel Kv1.1 (IC50 = 6.4 µM); does not inhibit diuresis in mice at 30 and 100 mg/kg due to low oral bioavailability and high hepatic clearance |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | VU-6036720 SUR-2b 1 |
Gene, Accession, CAS # | n/a |
Catalog # | 40286-1 |
Price | $74.00 |
Order / More Info | VU6036720 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |