Mizolastine from CAYMAN CHEMICAL COMPANY
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| Product Name | Mizolastine |
| Description | A histamine H1 receptor antagonist (Ki = 0.001 µM); selective for histamine H1 over histamine H2 and H3 receptors (Kis = >100 µM for both), as well as 5-HT1A , 5-HT1B, 5-HT1C, 5-HT1D, 5-HT2, and 5-HT3, dopamine D1 and D2, α1- and α2-adrenergic, adenosine, and muscarinic receptors in radioligand binding assays (Kis = >1 µM for all); reduces histamine release from bronchial mast cells in ovalbumin-sensitized guinea pigs at 0.1, 0.3, and 1 mg/kg; reduces histamine-induced paw edema in rats, skin edema in dogs, and bronchoconstriction in guinea pigs (ED50s = 0.5, 0.07, and 0.03 mg/kg, respectively); inhibits passive cutaneous anaphylaxis, as well as compound 48/80-induced lethal shock in rats (ED50s = 1.6 and 0.07 mg/kg, respectively) |
| Size | 5 g |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SL 850324 |
| Gene, Accession, CAS # | CAS: 108612-45-9 |
| Catalog # | 9000566-5 |
| Price | $595.00 |
| Order / More Info | Mizolastine from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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