Tat-CBD3 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY
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| Product Name | Tat-CBD3 (trifluoroacetate salt) |
| Description | An inhibitor of the Cav2.2-CRMP2 protein-protein interaction; inhibits the protein-protein interaction between CRMP2 and the NMDA receptor NR2B subunit; inhibits the Cav2.2-CRMP2 interaction by 43% in a cell-free assay and the NMDA receptor NR2B subunit-CRMP2 interaction in an immunoprecipitation assay at 10 µM; reduces voltage-induced calcium currents by approximately 60% in primary rat DRG neurons and glutamate-induced increases in cytosolic calcium levels in primary rat hippocampal neurons; decreases infarct volume in a rat model of MCAO-induced cerebral ischemia at 20 mg/kg; intrathecal administration prevents carrageenan-induced thermal hypersensitivity in rats,, |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1355359-36-2 TatCBD3 Cav2.2CRMP2 Cav 2.2 CRMP 2 ?YGRKKRRQRRRARSRLAELRGVPRGLOH CRM P2 NM DA NR 2B cyto solic |
| Gene, Accession, CAS # | n/a |
| Catalog # | 37448-25 |
| Price | $447.00 |
| Order / More Info | Tat-CBD3 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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