(−)-L-threo-PDMP (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | (−)-L-threo-PDMP (hydrochloride) |
| Description | An enhancer of ganglioside biosynthesis; increases glucosylceramide synthase activity by 4 and 8% at 5 and 2.5 µM, respectively, in an enzyme assay; increases the activity of ganglioside GM3, GD3, and GQ1b synthases and increases the levels of glucosylceramide, lactosylceramide, and ganglioside GM3 in B16 melanoma cells; inhibits the growth of MCF-7, MDA-MB-468, SK-BR-3 cells (IC50s = 4, 7, and 6 µM, respectively); increases neurite outgrowth and synapse formation in vitro and improves retention of a long-term memory learned prior to forebrain ischemia in rats at 40 mg/kg per day following ischemia |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 109836-81-9 monosialodihexosylganglioside antiganglioside |
| Gene, Accession, CAS # | CAS: 161491-04-9 |
| Catalog # | 10005278-5 |
| Price | $254.00 |
| Order / More Info | (−)-L-threo-PDMP (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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