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Product Name | A-1120 |
Description | An RBP4 antagonist (Ki = 8.3 nM for disruption of RBP4 binding to transthyretin); selective for RBP4 over CRBP1 (IC50s = 0.09 and >30 µM, respectively, in radioligand binding assays), as well as a panel of G protein-coupled receptors, kinases, and enzymes; reduces serum levels of RBP4 and retinol levels in mice at 30 mg/kg; inhibits retinal bisretinoid accumulation in the Abca4-/- mouse model of enhanced retinal lipofuscinogenesis-induced macular degeneration |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | A1120 RBP Abca 4 CRBP 1 nonretinoid |
Gene, Accession, CAS # | CAS: 1152782-19-8 |
Catalog # | 30921-5 |
Price | $121.00 |
Order / More Info | A-1120 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |