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Product Name | VS-5584 |
Description | A purine analog that inhibits mTOR (IC50 = 37 nM) and PI3K (IC50s = 16, 68, 25, and 42 nM for the α, β, γ, and δ isoforms, respectively); demonstrates broad anti-proliferative sensitivity leading to tumor growth inhibition in human tumor models |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | inhibitor mTOR PI3K antiproliferation antitumor cancer inhibit biochemical intracellular signaling kinase m-TOR anti-proliferation anti-tumor phosphatidylinositol 3-kinase Akt/PKB Akt PKB PI3K/mTOR mammalian target rapamycin gene expression cell differentiation apoptosis VS5584 purine analog α β γ δ isoform PI3Kα PI3Kβ PI3Kγ PI3Kδ phosphorylation substrate downstream board sensitivity tumor growth human model |
Gene, Accession, CAS # | CAS: 1246560-33-7 |
Catalog # | 16294-1 |
Price | $32.00 |
Order / More Info | VS-5584 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |