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Product Name | Fluvastatin (sodium salt hydrate) |
Description | An HMG-CoA reductase inhibitor (Ki = 0.3 nM for the rat enzyme); inhibits CYP2C9 (IC50 = 100 nM); inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in GPX4 and system Xc- levels in HUVECs; decreases serum cholesterol, triglyceride, and phospholipid levels, the formation of TBARS, and vascular ACE activity in rabbits fed a high-cholesterol diet at 2 mg/kg per day; increases survival in a mouse model of myocardial infarction at 10 mg/kg per day |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 93957-55-2 atherosclerosis HMG-CoA reductases LDL LDL-c HDL HDL-c statin cholesterol heart disease CVD inhibitors inhibits inhibition |
Gene, Accession, CAS # | n/a |
Catalog # | 10010337-10 |
Price | $26.00 |
Order / More Info | Fluvastatin (sodium salt hydrate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |