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Product Name | 25-hydroxy Cholesterol |
Description | An oxysterol; suppresses endogenous cholesterol synthesis by preventing SREBP transport to the Golgi; inhibits IgA class switching induced by LPS and various cytokines in B cells (IC50 = ~50 nM); inhibits replication of SARS-CoV-2 in Vero cells (EC50 = 3.675 µM); reduces viral RNA loads in the lung and trachea in a mouse model of SARS-CoV-2 infection at 100 mg/kg per day; serum levels are increased in hACE2 mice in a model of SARS-CoV-2 infection and in a patient with COVID-19 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 16505-96-7 anti-viral SARS-CoV-2 SARSCoV2 covid-19 covid19 coronavirus corona virus hydroxycholesterol 25-HC 25HC |
Gene, Accession, CAS # | CAS: 2140-46-7 |
Catalog # | 11097-5 |
Price | $33.00 |
Order / More Info | 25-hydroxy Cholesterol from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |