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Product Name | Vorasidenib |
Description | An inhibitor of mutant IDH (IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively); inhibits wild-type-IDH1R132H and wild-type-IDH2R140Q heterodimers (IC50s = 4 and 251 nM, respectively); decreases the production of 2-HG in TF-1 leukemia cells expressing IDH1R132H or IDH2R140Q (IC50s = 3.2 and 14 nM, respectively); reduces tumor growth in a TS603-IDH1R132H mouse xenograft model at 50 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AG-881 |
Gene, Accession, CAS # | CAS: 1644545-52-7 |
Catalog # | 28462-1 |
Price | $110.00 |
Order / More Info | Vorasidenib from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |